
Developing a greater understanding of the relationship between CUD and MDD is therefore important in order to help reduce the prevalence of both conditions through the efficient prevention and treatment of co-morbid cases.Ĭross-sectional studies of general and clinical populations consistently show that CUD and MDD co-occur at a rate greater than chance (see Degenhardt et al. The relationship between MDD and CUD is poorly understood, although individuals with co-morbid mental health and substance use disorders are particularly difficult to treat (Kessler 2004). Heavy cannabis use is linked to several adverse health outcomes (Hall and Degenhardt 2009 Hall 2015), and is the most commonly used illicit drug (Agrawal and Lynskey 2014). 2013), and the World Health Organization is now citing it as the leading one (WHO 2016). According to the latest Global Burden of Disease study in 2013, MDD was the 2nd leading cause of disability in the world (Ferrari et al. 2012) and highly relevant from a public health perspective. Major depressive disorder (MDD) and Cannabis use disorder (CUD) are co-morbid (see Degenhardt et al. Although the current study cannot differentiate between them statistically, these models, in combination, suggest that CUD risk factors may causally influence the risk to develop MDD, but only when risk for CUD is high. Both fit substantially better than the Correlated Liabilities model. Of the 13 different co-morbidity models, two fit equally well: CUD causes MDD and Random Multiformity of CUD. The analysis sample comprised 2410 male and female monozygotic and dizygotic twins (average age 32) who were assessed on CUD and MDD using the SSAGA-OZ interview. This study uses data from the Australian Twin Registry to compare 13 co-morbidity twin models initially proposed by Neale and Kendler (Am J Hum Genet 57:935–953, 1995).

Genetically informative studies can add valuable insight to this problem, as they allow the evaluation of competing models of co-morbidity. However, studies to date have not produced a clear understanding of the mechanisms underlying this co-morbidity. Some of the hottest women actors in the world.If you're curious to see what's going on with the hot lady twins, have a look at the hottest celebrity male twins.Cannabis use disorder (CUD) co-occurs with major depressive disorder (MDD) more frequently than would be expected by chance. These sexy twins are the hottest twin girls in hollywood. if your favorite celebrity twins aren't on the list, make sure to add them and vote them up on this list of twins. Vote up your favorite hot twins and keep an eye on that #1 sexiest twins spot.

Who are the sexiest female celebrity twins? Who are the hottest famous sisters? This round-up of famous and hot female twins is here for your voting pleasure so a consensus can be reached as to who the best celeb twins really are.
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Genetics have blessed these hot celebrity sisters and we are all better for getting to behold the likes of Cynthia and Brittany Daniel on our TV and movie screens at our leisure. Whether you're into the smoldering good looks of Patricia and Gisele Bundchen or the impish charm of Mary Kate and Ashley Olsen (remember when they were on TV in diapers?), there are myriad hot celebrity twins on this list to keep you occupied.

Seeing double never felt so good (or medically unalarming). These hot celebrity twins come from the worlds of modeling, acting, and sports and are will make your heart beat twice as fast as you gaze upon their hotness. Believe it or not, among the most beautiful women in the world are twins.

You know what's better than one hot celebrity? Two.
